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Myelin Basic Protein MBP
CAS No. 126768-94-3
Myelin Basic Protein MBP( —— )
Catalog No. M30349 CAS No. 126768-94-3
Myelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the nervous system.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameMyelin Basic Protein MBP
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NoteResearch use only, not for human use.
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Brief DescriptionMyelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the nervous system.
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DescriptionMyelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the nervous system.
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In VitroOnce MBP4-14 is phosphorylated, it is not dephosphorylated by okadaic acid-sensitive phosphatases (protein phosphatases 1, 2A and 3) or other protein phosphatases such as calcineurin and/or PP 2C present in hippocampal homogenates. Therefore, MBP4-14 can be used for PKC assay in crude extracts of neural tissue.
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetPKC
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number126768-94-3
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Formula Weight1390.59
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Molecular FormulaC60H103N21O17
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameSequence:{Gln}{Lys}{Arg}{Pro}{Ser}{Gln}{Arg}{Ser}{Lys}{Tyr}{Leu}
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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HG-9-91-01
HG-9-91-01 is a potent and highly selective salt-inducible kinase (SIKs) inhibitor with?IC50s of 0.92 nM, 6.6 nM and 9.6 nM for?SIK1, ?SIK2?and?SIK3respectively.
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20-HETE
20-HETE promotes cell proliferation and migration in cancer and can be used to study prostate tumors and cardiac hypertrophy by activating the protein kinase C pathway to increase FBXO10 expression.
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ZIP
Novel, cell-permeable inhibitor of protein kinase Mζ (PKMζ), a constitutively active, atypical PKC isozyme involved in LTP maintenance. Selectively blocks PKMζ-induced synaptic potentiation in hippocampal slices in vitro. Reverses late-phase LTP (IC50 = 1 - 2.5 μM) and produces persistent loss of 1-day-old spatial memory following central administration in vivo.
